The Wang Lab at the Division of Hematology & Oncology, Columbia University Irving Medical Center, studies how dysregulation of RNA splicing and modifications drives the development and progression of B cell malignancies, with a focus on chronic lymphocytic leukemia (CLL). Using integrative multi-omics approaches and patient-derived models, we aim to uncover how abnormal RNA regulation reshapes gene expression, tumor–microenvironment interactions, and therapeutic responses. Our goal is to translate mechanistic insights into clinically actionable biomarkers and treatment strategies for patients with B cell cancers.

News

  • Aug 2026: Congratulations Ilana on your T32 fellowship!
  • Aug 2026: Welcome Meagan as our lab manager!
  • Jul 2026: Welcome George to join our team!
  • Jun 2026: Wang Lab welcomes Xiaojie, Alexandra, and Matthew, and congratulates Prajish on his first Columbia pilot grant.

Join us!

We are hiring for postdoctoral fellows and computational biologists.